Advancements in biomedical sensing through integrated optical endo-microscopy systems

Abstract

Monitoring physiological changes in living organisms presents significant challenges, necessitating the use of specialised analytical tools. Fibre-optic probes provide a minimally invasive means for detecting physiological signals from precise locations within the body. Advancements in fibre probe-based sensing and imaging are crucial to biomedical fields, achieving transformative outcomes through interdisciplinary collaboration. Key attributes of fibre optics for in vivo imaging and sensing include their compact dimensions and inert glass composition, enabling minimally invasive clinical applications and deep tissue, non-destructive probing. Moreover, approximately one in twelve adults suffer from chronic obstructive pulmonary disease (COPD) or asthma, with acute exacerbations of chronic lower respiratory diseases (CLRDs) being the leading causes of mortality and morbidity. Effective methods for detecting exacerbations and cases within populations are vital for advancing prevention research. This study demonstrates the potential of integrating biomedical and fibre-optic research in an educational and engaging manner for non-specialist audiences. It aims to enhance understanding of lung diseases using novel techniques based on optical endo-microscopy (OEM). The study has improved engagement activities, bridging theoretical concepts with practical applications. These activities include the development of cost-effective educational tools adapted from medical OEM technologies, facilitating the dissemination of advanced scientific knowledge to a broader audience