Using NMR, X-ray, and CD analysis in the study on natural products obtained from Vietnamese plant and fungi in terms of pharmaceutical product development

Authors

  • Dinh Thang Tran* Faculty of Chemistry, Vinh University, Vietnam
  • Cong Dung Vo Faculty of Chemistry, Vinh University, Vietnam
  • Ngoc Tuan Nguyen Faculty of Chemistry, Vinh University, Vietnam
  • Manh Dung Doan Faculty of Chemistry, Hue University of sciences - Hue University, Vietnam
  • Yang-Chang Wu School of Pharmacy, College of Pharmacy, China Medical University, Taiwan
  • Tian-Shung Wu School of Pharmacy, National Cheng Kung University, Taiwan

Abstract

NMR, X-ray analysis, and CD methods are powerful techniques for the study of absolute configuration of bioactive compounds from natural resources. This study presents the results of a joint-study between Vietnam and Taiwan on the bioactive compounds obtained from Vietnamese plants and fungi. Among the tested compounds, hexatenuin A displayed the most significant inhibition of superoxide anion generation and elastase release. These triterpenoids may be used as potential anti-inflammatory agents.

Keywords:

absolute configuration, circular dichroism, NMR, X-ray analysis

DOI:

https://doi.org/10.31276/VJSTE.59(4).14

Classification number

2.2

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Published

2017-12-15

Received 8 June 2017; accepted 7 November 2017

How to Cite

Dinh Thang Tran, Cong Dung Vo, Ngoc Tuan Nguyen, Manh Dung Doan, Yang-Chang Wu, & Tian-Shung Wu. (2017). Using NMR, X-ray, and CD analysis in the study on natural products obtained from Vietnamese plant and fungi in terms of pharmaceutical product development. Vietnam Journal of Science, Technology and Engineering, 59(4), 14-20. https://doi.org/10.31276/VJSTE.59(4).14

Issue

Vol. 59 No. 4 (2017)

Section

Physical Sciences

License

This work is licensed under a Attribution-NonCommercial-NoDerivatives 4.0 International

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