Effective treatment for symptomatic brain tumours and arteriovenous malformation in children by radiosurgery with a rotating gamma system

Authors

  • Khoa Mai Trong Hanoi Medical University
  • Phuong Pham Cam* The Nuclear Medicine and Oncology Centre, Bach Mai Hospital
  • Luan Nguyen Duc The Nuclear Medicine and Oncology Centre, Bach Mai Hospital
  • Hung Nguyen Quang The Nuclear Medicine and Oncology Centre, Bach Mai Hospital
  • Phuong Dao Manh The Nuclear Medicine and Oncology Centre, Bach Mai Hospital
  • Thai Pham Van Hanoi Medical University

Keywords:

arteriovenous malformation, brain tumours in children, headache, hemiplegia, radiosurgery, rotating gamma system, seizures, symptom relief

Abstract

To assess the effectiveness of radiosurgery with a rotating gamma system (RGS) for paediatric brain tumours and arteriovenous malformation (AVM), this work was carried out on 123 patients with brain tumours or AVM received radiosurgery at Bach Mai hospital. The median dose was 13 Gy from a range of 8 to 20 Gy. Endpoints include the effects of increased intracranial pressure, seizures, hemiplegia, and tumour size on the syndrome. Results exhibited that the percentages of patients with complete response, partial response, and disease progression out of 59 patients with headache accounted for 11.9, 69.5, and 18.6%, respectively. Of the 20 patients with seizures, 30% had complete response, 65% partial response, and 5% stable disease. Regarding brain tumour size, 9 months after treatment, those with complete response, partial response, stable disease, and disease progression made up 18.7, 50.4, 14.6, and 16.3% of the total patients, respectively. There was no statistically significant effect of radiation dose on the results. This study showed a high percentage of children with brain tumours and AVM undergoing radiosurgery with a RGS had symptomatic responses after treatment.

DOI:

https://doi.org/10.31276/VJSTE.64(3).44-48

Classification number

3.2

Downloads

Published

2022-09-15

Received 1 October 2021; accepted 3 December 2021

How to Cite

Khoa Mai Trong, Phuong Pham Cam, Luan Nguyen Duc, Hung Nguyen Quang, Phuong Dao Manh, & Thai Pham Van. (2022). Effective treatment for symptomatic brain tumours and arteriovenous malformation in children by radiosurgery with a rotating gamma system. Vietnam Journal of Science, Technology and Engineering, 64(3), 44-48. https://doi.org/10.31276/VJSTE.64(3).44-48

Issue

Section

Life Sciences