Chemical constituents isolated from stems of Maesa membranacea

Nguyen Thanh Le^1*, Huu Giap Tran¹, Thi Kim Oanh Vu¹, Thuy Duong Pham², Ngoc Thuc Dinh³, Anna Stojakowska⁴, Bich Ngan Truong¹

¹Institute of Marine Biochemistry, Vietnam Academy of Science and Technology, Vietnam

²College of Science and Engineering, Texas Christian University, USA

³Department of Science and Technology Management, Hong Duc University, Vietnam

⁴Institute of Pharmacology, Krakow, Poland

Received 16 March 2020; accepted 8 June 2020

 

Abstract:

Maesa membranacea A. DC. (Myrsinaceae) has been traditionally used for the treatment of fever and hepatitis. The phytochemical investigation of Maesa membranacea stems has led to the isolation of six compounds including kaempferol (1), (-)-epicatechin (2), betulinic acid (3), p-hydroxybenzoic acid (4), vanilic acid (5), and protocatechuic acid (6). The chemical structures of these compounds have been determined by nuclear magnetic resonance (NMR), mass spectrometry (MS) data, and by comparison with previously reported works. This is the first report of a chemical study on Maesa membranacea as compounds 1-6 listed above were found from the Maesa genus for the first time.

Keywords: flavonoids, Maesa membranacea, phenolic acids, triterpene.

Classification number: 2.2